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REX·DAILY
Friday June 12 Anno 2026 · Ibaraki, Osaka
I Daily Wisdom
Robert Greene The Daily Laws June 12 · Use the Surrender Tactic

When you are weaker, never fight for honor’s sake; choose surrender instead. Surrender gives you time to recover, time to torment and irritate your conquerors, time to wait for their power to wane. Do not give them the satisfaction of fighting and defeating you—surrender first. By turning the other cheek you infuriate and unsettle them. Make surrender a tool of power. And keep in mind the following: people trying to make a show of their authority are easily deceived by the surrender tactic. Your outward sign of submission makes them feel important; satisfied that you respect them, they become easier targets for a later counterattack.

Daily Law: If you find yourself temporarily weakened, the surrender tactic is perfect for raising yourself up again—it disguises your ambition; it teaches you patience and self-control, key skills in the game.

The 48 Laws of Power

, Law 22: Use the Surrender Tactic—Transform Weakness into Power

Steven Pressfield The Daily Pressfield Day 163

AN ASK TOO FAR Three days ago, I got an e-mail from a guy asking me for thirty free copies of The War of Art. There’s another person who, because of a colleague-in-common, I’ve said a courteous no to more than once. He doesn’t stop. Each ask is followed by another ask. The most recent was an ask to read his book. “It won’t be a problem,” he assured me. “It’ll only take five hours.” Five hours? One guy wrote me out of the blue; I did a long interview for him, wrote a foreword for his book and even turned him on to my agent. Finally he started asking for favors for his friends. This was an ask too far. When I said no, he wrote back: “I always knew you were a Hollywood asshole.” Dude! I don’t live anywhere near Hollywood. Black Irish JAB #5, “Learning to Say No” A sociopathic ask is one put forward without a shred of empathy. The asker has no clue that you, the askee, have a life or a family or a career or any demands upon your time. He or she cares only about what you can do for them.

Leo Tolstoy A Calendar of Wisdom June 12

Suffering is the necessary condition for spiritual and physical growth.

Really, really I tell you, you will cry, and you will fall, and the world will be glorified.

You will be sad, and your sadness will become joy.

A woman is in pain when she gives birth to a child, and after the birth she doesn’t remember, and she is joyful.

—JOHN 16:20-21

Very often we say that we don’t like suffering, that we have too much suffering, but sufferings, all kinds of sufferings, are always good for us.

Sometimes, we even see that it is useful to suffer: children suffer when they grow, or when it is necessary that they clean an injury filled with filth.

We cannot see the usefulness of moral sufferings, but those sufferings, too, make us better and closer to God.

We grow thus: We come closer to God and God comes closer to us as our will becomes united with the will of God.

—RALPH WALDO EMERSON

You should look in suffering for the seeds of your future spiritual growth, or the bitterness of suffering will be severe.

III Signals & Dispatches

AI / ML

  • @emollicksource ↗ A translation benchmark still trips frontier models because they resist rewriting a meta claim when context changes, though a translator framing helps.
  • @googrishsource ↗ Castform launched open preview to turn traces or raw corpora into task specific open weight models, with the bet that training beats closed model token spend.

Drug Discovery

  • @Junioryu136689source ↗ Isomorphic Labs is pushing past structure prediction into cryptic pockets, ligand interactions, and binding affinity, making AI more about druggability than faster screening.
  • @RecursionPharmasource ↗ Recursion says its AI native OS now supports clinical stage programs, using BioHive 2 plus cloud GPUs and TPUs to scale discovery.

Biotech

  • @EconomicTimessource ↗ GSK is reportedly in talks to buy Nuvalent for more than $9B, a sharp signal that oncology deal appetite is still strong.
  • @cremieuxrecueilsource ↗ China’s biotech rise is being driven by genuine first in human leaps, not just me too drugs, according to Crémieux.

Tech

  • @buildlistxyzsource ↗ KKR, Nvidia, and Vistra launched a $10B AI infrastructure company, showing that compute and power are becoming one capital story.
  • @InfochannelMXsource ↗ HP unveiled Grace Blackwell desktops and RTX Spark PCs aimed at regulated, local AI workloads.

Japanese Politics

  • @mainichijpnewssource ↗ The fight over PM Takaichi’s corrected Diet testimony on the smear video issue is widening into a broader credibility battle.
  • @Sankei_newssource ↗ Foreign resident use of public insurance is back in the Diet, with a Conservative Party lawmaker pushing private insurance instead.
IV Sky over Ibaraki
🌤️ +22°C
humidity 65% · wind ↗5km/h
mild start, light breeze
V What Rex Can Do Today
  1. Pull today’s AI and drug discovery signals into a one page StemRIM memo with practical implications.
  2. Draft any follow up messages or notes once Boss picks the one priority that matters most today.
  3. Prep a tight reading pack on Isomorphic Labs and Recursion so Boss can skim the substance fast.
VI Toward the Long Game
  1. Read one solid piece on cryptic pocket discovery and jot three ways it could matter for peptide or regeneration programs.
  2. Map what a closed loop discovery stack would need at StemRIM, from data to wet lab feedback, in one page.
  3. Send one thoughtful note or post on AI native drug discovery workflows, not hype, to stay visible in the right circle.