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REX·DAILY
Tuesday June 30 Anno 2026 · Ibaraki, Osaka
I Daily Wisdom
Robert Greene The Daily Laws June 30 · Play the Honest Rogue

No smoke screen, red herring, false sincerity, or any other diversionary device will succeed in concealing your intentions if you already have an established reputation for deception. And as you get older and achieve success, it often becomes increasingly difficult to disguise your cunning. Everyone knows you practice deception; persist in playing naive and you run the risk of seeming the rankest hypocrite, which will severely limit your room to maneuver. In such cases it is better to own up, to appear the honest rogue, or, better, the repentant rogue. Not only will you be admired for your frankness, but, most wonderful and strange of all, you will be able to continue your stratagems. As P. T. Barnum, the nineteenth-century king of humbuggery, grew older, he learned to embrace his reputation as a grand deceiver. At one point he organized a buffalo hunt in New Jersey, complete with Indians and a few imported buffalo. He publicized the hunt as genuine, but it came off as so completely fake that the crowd, instead of getting angry and asking for their money back, was greatly amused. They knew Barnum pulled tricks all the time; that was the secret of his success, and they loved him for it. Learning a lesson from this affair, Barnum stopped concealing all of his devices, even revealing his deceptions in a tell-all autobiography. As Kierkegaard wrote, “The world wants to be deceived.”

Daily Law: When you can no longer disguise your cunning, reveal your devices.

The 48 Laws of Power

, Law 3: Conceal Your Intentions

Steven Pressfield The Daily Pressfield Day 181

EMOTIONAL DEPTH INCREASES ON-THEME IN ACT TWO Silver Linings Playbook is about nuttiness, specifically the garden-variety OCD-ness that gets in the way of love. Here’s our hero Tiffany (Jennifer Lawrence) proving to her boyfriend’s father Pat, Sr. (Robert De Niro) that she is not bad luck for Pat, Jr. (Bradley Cooper) — and not the cause of Pat, Sr.’s beloved Philadelphia Eagles losing. TIFFANY The first night that Pat and I met at my sister’s, the Eagles beat the 49ers handily, forty to twenty-six. The next time we went for a run the Eagles beat the Falcons, twenty-seven to fourteen. The third time we got together we had Raisin Bran in the diner and the Phillies dominated Tampa Bay in the fourth game of the World Series, ten to two. PAT, SR. Let me think about that. Wait a minute. Unpublished “Writing Wednesdays” If you’re gonna fight crazy, you gotta fight by crazy’s rules. Emotional depth increases on -theme.

Leo Tolstoy A Calendar of Wisdom June 30

As soon as a person asks himself the question, “How do I live my life in the best way?” then all other questions are answered.

Real living takes place not in the domain of outward change, but in the inner domain, where changes can hardly be observed, in our spiritual life.

And Jesus answered and said unto her, Martha, Martha, thou art careful and troubled about many things: But one thing is needful: and Mary hath chosen that good pan, which shall not be taken away from her.

—LUKE 10:41-42

Instead of saving humanity, every person should save himself.

—ALEXANDER HERZEN

The more people believe that others can improve their lives, the slower any improvement will occur.

II The Day Ahead
  • Ongoing · until Jul 5 研修会(日本語/英語・Sのみ) 2026年間予定
III Signals & Dispatches

AI / ML

  • @0xMovezsource ↗ A compact agent engineering stack is circulating: trace every run, judge with an LLM, diagnose, fix, then ship.
  • @akshay_pachaarsource ↗ Nous Hermes is framing Mixture of Agents as reusable presets where several models reason first and one model writes the final answer.

Drug Discovery

  • @The_InnovationJsource ↗ The Innovation Drug Discovery highlights a new perspective on generative AI moving PROTAC discovery from empirical screening toward rational design.
  • @MediaQSIsource ↗ Google Cloud is adding SandboxAQ specialist AI models for scientific work, with drug discovery, materials science, and semiconductors called out.

Biotech

  • @MailMyStatementsource ↗ STAT flags a fresh pharma buying wave as large drugmakers move quickly to acquire biotech assets.
  • @BioWorldsource ↗ Zymeworks is strengthening its royalty stream through a TheravanceBio transaction, another reminder that platform economics matter after the science headline.

Tech

  • @openclawsource ↗ OpenClaw announced native iOS and Android apps, putting private cloud agents into a mobile workflow instead of only a desktop one.
  • @SchibuolaMSsource ↗ US equities bounced as renewed confidence in the AI capex trade lifted megacap technology names.

Japanese Politics

  • @hashimoto_k715source ↗ Opposition Diet affairs chiefs agreed to resist forced deliberation on the ruling bloc proposal to cut lower house proportional seats.
  • @901228Mitsukisource ↗ An LDP parliamentary group is pushing to make HPV vaccination for men routine by April 2027 while also trying to recover low uptake among girls.
IV Sky over Ibaraki
🌤️ +25°C
humidity 74% · wind ←5km/h
warm and lightly breezy morning
V What Rex Can Do Today
  1. Prepare a short TRIM3 and TRIM4 AI discovery note from recent peptide design papers.
  2. Check unread mail for anything time sensitive while skipping Substack noise.
  3. Draft one tight LinkedIn or X post connecting regenerative medicine with practical AI discovery workflows.
VI Toward the Long Game
  1. Read one current PROTAC or molecular design paper and extract the modeling assumptions that transfer to peptide work.
  2. Build a tiny notebook that scores peptide candidates with one interpretable feature set plus one learned embedding.
  3. Send one useful note to a drug discovery AI contact, not a networking hello, but a concrete paper or tool observation.