Tuesday, August 25 — Rex Daily

I Daily Wisdom

Robert Greene The Daily Laws August 25 · Cultivate the Third Eye

In 401 BC, ten thousand Greek mercenary soldiers suddenly found themselves on the losing side of a battle, trapped deep in the heart of Persia. They wandered through their camp bemoaning their fate. Among them was the writer Xenophon, who had gone along with the soldiers as a kind of roving reporter. Xenophon had studied philosophy as a student of Socrates. He believed in the supremacy of rational thinking, of seeing the entire picture, the general idea behind the fleeting appearances of daily life. One night he had a vision of how the Greeks could escape their trap and return home. He saw them moving swiftly and stealthily through Persia, sacrificing everything for speed. He saw them leaving right away, using the element of surprise to gain some distance. He thought ahead—of the terrain, the route to take, the many enemies they would face, how they could help and use citizens who revolted against the Persians. In the space of a few hours, he had conjured up the details of the retreat, all inspired by his overall vision of their fast zigzag route to the Mediterranean and home. Although he had no military experience, his vision was so complete, and he communicated it with such confidence, that the soldiers nominated him as their de facto leader. This story embodies the essence of all authority and the most essential element in establishing it. Most people are locked in the moment. They are prone to overreacting and panicking, to seeing only a narrow part of the reality facing the group. They cannot entertain alternative ideas or prioritize. Those who maintain their presence of mind and elevate their perspective above the moment tap into the visionary powers of the human mind and cultivate that third eye for unseen forces and trends. They stand out from the group and fulfill the true function of leadership.

Daily Law: Create the aura of authority by seeming to possess the godlike ability to read the future. This is a power that can be practiced and developed and applied to any situation.

The Laws of Human Nature

, 15: Make Them Want to Follow You—The Law of Fickleness

Steven Pressfield The Daily Pressfield Day 237

THE ALL IS LOST MOMENT REDUCES THE HERO TO HIS CORE In Hidalgo, Viggo Mortensen plays Frank Hopkins, the true historical long-distance horse racer. Hidalgo is Frank’s unbeatable mustang pony. In the film, Hopkins and Hidalgo compete against the finest purebred Arabian horses in a three-thousand-mile race across Arabia, Iraq, and Syria in the last decade of the nineteenth century. The All Is Lost Moment comes within sprinting distance of the finish when Hidalgo collapses from exhaustion, at the point of death. Hopkins literally has his.45 cocked, ready to put his beloved mount out of its misery. Hopkins himself is in a near-hallucinatory state from fatigue, heat, and dehydration. In other words, our hero has been reduced to the naked core of his being. Unpublished Black Irish JAB, “The All Is Lost Moment” The purpose of the All Is Lost Moment is to break the hero down to his or her emotional, moral, and spiritual essence. This is where we and our readers find out what our protagonist is really made of.

Leo Tolstoy A Calendar of Wisdom August 25

Work is the condition of existence in the material, physical world.

If Robinson had not worked, he would have frozen to death and died from hunger, and everybody can see this.

So labor is the necessary condition for the spiritual life as well, but not all people can see this clearly, though it is as obvious as the necessity of physical labor for the body.

If any would not work, neither should he eat.

—II THESSALONIANS 3:10

If you are doing nothing, it means you are doing bad things.

Those who do nothing, do bad things.

Those who do nothing, have many associates and supporters.

The brain of a lazy and idle person is the favorite stopping place of the devil.

Nature does not stop in its development, and it executes all kinds of idleness.

—JOHANN WOLFGANG VON GOETHE

You should never be ashamed of any work, even the lowest and dirtiest, but you should be ashamed only of the dirtiest moral state, that is the idleness of your body, which is the necessary result of the consumption of the labor of others.

II The Day Ahead

Today · all day Jakarta trip with Minori and Eisuke ewijaya@gmail.com
Today · 09:00 Keep Telkomsel SIM alive: attach to a network or send an SMS ewijaya@gmail.com

III Signals & Dispatches

AI / ML

@ai_catchup_jp source ↗ Anthropic is reportedly preparing an IPO filing by late August, a test of how public markets value the next wave of AI businesses.
@askalphaxiv source ↗ OpenResearch now turns a research idea into an experiment tree and LaTeX paper with Claude Code or Codex agents in one workspace.

Drug Discovery

@zachorsomthin source ↗ Fine tuned TxGemma 9B reached ROC AUC 0.731 on early malaria drug screening versus 0.499 without fine tuning, beating Gemini 2.5 and o3 in the comparison.
@genbioai source ↗ In context molecular design aims to target specific changes in cell state and characterize the intervention through multimodal readouts.

Biotech

@StockWireX source ↗ The EU Commission reportedly approved DAYBU as the first Rett syndrome treatment across 30 markets, triggering a 35 million dollar payment on German launch.
@Arioste5563 source ↗ Experts say pharmaceutical tariffs are creating uncertainty and forcing biotech companies to rethink their operating playbooks.

Tech

@ar10nx source ↗ Elon Musk says SpaceX now delivers about 85 percent of payload to Earth orbit, suggesting infrastructure dominance rather than startup scale disruption.
@linasbeliunas source ↗ Patrick Collison and Mario Draghi launched the Rhine Group with about 55 experts to push European competitiveness reforms outside slow official machinery.

Japanese Politics

@0W8x2 source ↗ A Diet discussion argues that fiscal consolidation and the loss of public spending power are part of why Japanese wages remain stagnant.
@garmy source ↗ A new Japanese debate says the delayed release and planned repurchase of reserve rice became a policy failure that unsettled both consumers and producers.

IV Sky over Ibaraki

V What Rex Can Do Today

Pull the strongest AI drug discovery papers from the last seven days and write a one page note on relevance to StemRIM.
Review current project folders for stale drafts and surface one high value cleanup or follow up.
Draft a short post connecting regeneration inducing medicine with the latest AI biology trend, without publishing it.

VI Toward the Long Game

Read the TxGemma malaria screening study and reproduce its ROC AUC comparison in a small notebook.
Work through one Stanford EE364A lecture and formulate peptide candidate selection as variables, an objective, and constraints.
Study in context molecular design and write one paragraph mapping it to cell state and regenerative medicine.