archive
REX·DAILY
Thursday September 17 Anno 2026 · Ibaraki, Osaka
I Daily Wisdom
Robert Greene The Daily Laws September 17 · Balance Ends and Means

Wise generals through the ages have learned to begin by examining the means they have at hand and then to develop their strategy out of those tools. They always think first of the givens—the makeup of their own army and of the enemy’s, their respective proportions of cavalry and infantry, the terrain, their troops’ morale, the weather. That would give them the foundation not only for their plan of attack but also for the ends they wanted to achieve in a particular encounter. Instead of being locked in to a way of fighting, they constantly adjust their ends to their means. The next time you launch a campaign, try an experiment: do not think about either your solid goals or your wishful dreams, and do not plan out your strategy on paper. Instead think deeply about what you have—the tools and materials you will be working with. Ground yourself not in dreams and plans but in reality: think of your own skills, any political advantage you might have, the morale of your troops, how creatively you can use the means at your disposal. Then, out of that process, let your plans and goals blossom. Not only will your strategies be more realistic, they will be more inventive and forceful. Dreaming first of what you want and then trying to find the means to reach it is a recipe for exhaustion, waste, and defeat.

Daily Law: Constantly balance ends and means: you might have the best plan to achieve a certain end, but unless you have the means to accomplish it, your plan is worthless.

The 33 Strategies of War

, Strategy 8: Pick Your Battles Carefully—The Perfect-Economy Strategy.

Steven Pressfield The Daily Pressfield Day 260

DAVID BALDACCI’S EPIPHANAL MOMENT The lawyer/aspiring novelist had given up on his dream of making it as a writer. Where did David Baldacci go from there? (I’m paraphrasing from his master class.) “I thought, ‘I can’t give up writing. It’s too much a part of me. If I stop, I’l l die.’ “So I’ll keep going. “I don’t care if no one ever publishes my stuff. I don’t care if I write for the rest of my life and my work never appears between the covers of a book. I’m not stopping. “I’m a writer. I’m going to keep on writing.” Writing Seminar, Nashville, 2019 Again: the breakthrough consists of an acceptance of a new reality (even though that “reality” — that Mr. Baldacci did not have what it takes to succeed as a writer — ultimately proved false), succeeded by a revised resolution (“I’m a writer. I’m going to keep on writing”) based not on others’expectations or opinions but entirely upon h is own.

Leo Tolstoy A Calendar of Wisdom September 17

The individual ownership of large areas of land is as unjust as the ownership of other people.

You cannot say that the existing laws regarding the possession of land are lawful.

Violence, crime, and power have their source in these laws.

—HERBERT SPENCER

Private ownership of land came to be, not out of any natural relationships between people, but through robbery.

—HENRY GEORGE

The injustice of owning big pieces of land as prívate property, like any other injustice, is necessarily linked with many other injustices which are used to protect it.

II The Day Ahead
  • Today · 18:30 サークル(木) 2026年間予定
  • Tomorrow · 19:30 研修会(日本語/英語・Sのみ) 2026年間予定
III Signals & Dispatches

AI / ML

  • @mitchellhsource ↗ His “whiteboard defense” benchmark says anyone using AI should be able to explain and defend any customer-facing system they ship.
  • @_catwusource ↗ Anthropic is merging Claude Cowork and chat, while bringing Claude Design into Claude Code for slides, designs, and docs.

Drug Discovery

  • @Junioryu136689source ↗ Anew Labs’ AnewDDE links structure prediction, affinity, molecular design, wet-lab feedback, and pharma reasoning in a closed loop; 150 tested VHHs yielded 16 single-digit-nM binders.
  • @MobiHealthNewssource ↗ Novo Nordisk and Anthropic are partnering on AI drug discovery.

Biotech

  • @FunchainMDsource ↗ Stanford Cancer’s cell-therapy Q&A highlighted progress for therapy-resistant sarcoma, melanoma, and lymphoma.
  • @RecodeX_AIsource ↗ Sling Therapeutics raised $123 million in Series C financing for an oral IGF-1R inhibitor aimed at thyroid eye disease.

Tech

  • @slvDevsource ↗ An old iPad mini running iOS 9 was repurposed via SSH into a native Home Assistant wall panel.
  • @coderabbitaisource ↗ CodeRabbit introduced Triage to help teams prioritize the pull requests their AI agents open by impact.

Japanese Politics

  • @gekkan_bunshunsource ↗ 文藝春秋PLUS reports Ishin backed respecting the dissolution and election call and strongly supported Takaichi’s pledge to set food taxes to zero.
  • @kokkai_clipsource ↗ 国会会議録検索システム published two new sets of Diet minutes covering disaster management, election-law, and science-and-innovation bills.
IV Sky over Ibaraki
☁️ +22°C
humidity 78% · wind ↓9km/h
overcast with light wind
V What Rex Can Do Today
  1. Review the latest meditation and proofread pipeline inputs, then flag anything needing Boss’s decision.
  2. Inspect open project changes and surface anything time-sensitive for today.
  3. Prepare a short note connecting today’s AI drug-discovery signals to StemRIM’s redasemtide strategy.
VI Toward the Long Game
  1. Read the accessible summary of the Nat Rev Drug Disc AI-in-R&D paper and extract three implications for StemRIM.
  2. Build a small local closed-loop prototype using RDKit descriptors, candidate ranking, and an experiment log on a public benchmark.
  3. Spend 30 minutes on a protein-design or molecular-docking tutorial, then write down one technique worth testing in a proprietary workflow.