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REX·DAILY
Wednesday September 23 Anno 2026 · Ibaraki, Osaka
I Daily Wisdom
Robert Greene The Daily Laws September 23 · Develop Your

Fingerspitzengefühl

Presence of mind depends not only on your mind’s ability to come to your aid in difficult situations but also on the speed with which this happens. Waiting until the next day to think of the right action to take does you no good at all. “Speed” here means responding to circumstances with rapidity and making lightning-quick decisions. This power is often read as a kind of intuition, what the Germans call

Fingerspitzengefühl

(fingertip feel). Erwin Rommel, who led the German tank campaign in North Africa during World War II, had great fingertip feel. He could sense when the Allies would attack and from what direction. He didn’t just study his men, his tanks, the terrain, and the enemy—he got inside their skin, understood the spirit that animated them, what made them tick. Having felt his way into these things, in battle he entered a state of mind in which he did not have to think consciously of the situation. The totality of what was going on was in his blood, at his fingertips. He had

Fingerspitzengefühl

. Whether or not you have the mind of a Rommel, there are things you can do to help you respond faster and bring out that intuitive feel that all animals possess. Deep knowledge of the terrain will let you process information faster than your enemy, a tremendous advantage. Getting a feel for the spirit of men and material, thinking your way into them instead of looking at them from outside, will help to put you in a different frame of mind, less conscious and forced, more unconscious and intuitive.

Daily Law: Get your mind into the habit of making lightning-quick decisions, trusting your fingertip feel. And you will develop this by knowing as deeply as possible all the details in any situation.

The 33 Strategies of War

, Strategy 3: Amidst the Turmoil of Events, Do Not Lose Your Presence of Mind—The Counterbalance Strategy

Steven Pressfield The Daily Pressfield Day 266

EPIPHANAL MOMENT = START OF ARTIST’S JOURNEY In this moment, the hero experiences a breakthrough. This breakthrough is almost always internal. The hero changes her attitude. She regroups. She sees her dilemma from a new perspective, one she had never considered before (or, if she had considered it, had rejected), a point of view that offers either hope or desperation amounting to hope. The movie now enters Act Three. The hero, fortified by this fresh hope (or desperation), charges full-tilt into the climax. The Artist’s Journey, p. xiv Our real-life Act Two ends with our acknowledgment of our true calling. What will be the content of our Act Three? If you’re an artist, I can tell you right now. Act Three will be you producing the works you were put on this Earth to bring forth.

Leo Tolstoy A Calendar of Wisdom September 23

No matter how big mankind’s store of knowledge seems to me in comparison with our previous ignorance, it is only an infinitely small part of all possible knowledge.

Socrates did not have the weakness of many scholars, the desire to know about all possible things, to learn the origins and explanations of things—what the Sophists call “the nature of things”—and to uncover the origins of the celestial bodies.

Socrates said, “Is it true that people are so concerned with these earthly things?

People wrongly think that they should know everything.

They think that they can despise the most necessary and important fields of knowledge, and penetrate the mysteries that do not belong to us.”

—XENOPHON

Not only is real science not hostile to religion, in fact real science always supports it.

—JOHN RUSKIN

Knowledge is limitless, and the most scholarly and educated person is as far from true knowledge as an uneducated peasant.

—JOHN RUSKIN

We cannot imagine the scope of our ignorance, just as a blind man cannot imagine darkness until he can see.

—IMMANUEL KANT

It is better to know less than necessary than to know more than necessary.

Do not fear the lack of knowledge, but truly fear unnecessary knowledge which is acquired only to please vanity.

II The Day Ahead
  • Today · all day Autumn Equinox Holidays in Japan
  • Today · ongoing 研修会(日本語/英語・Sのみ) 2026年間予定
III Signals & Dispatches

AI / ML

  • @claudeaisource ↗ Anthropic announced Claude Opus 5.5, a new model in the Claude 5.5 family positioned as matching Fable 5.1 performance at 40% lower cost.
  • @yaoyoroztechsource ↗ AWS and Salesforce are collaborating to address data fragmentation, a major barrier to enterprise AI-agent adoption.

Drug Discovery

  • @earlysignalsvcsource ↗ Big Picture Bio’s generative world model reportedly called 12 of 14 Phase 3 oncology readouts before the data, including Regeneron’s fianlimab failure.
  • @Kardashev001source ↗ A case study claims an allele-specific ASO/siRNA workflow cut specialist work from $12,000+ and a week to about $100 of compute and an hour, with assay and delivery still limiting.

Biotech

  • @BadSignalAIsource ↗ Ramona Optics raised a $25M Series A to scale multi-camera AI microscopy for living biology and drug discovery.
  • @0xWast3source ↗ An AI analysis reportedly used residue-by-residue pocket matching and human-variant modeling to rank antibiotics at risk of hitting human ribosomes.

Tech

  • @TWiTsource ↗ Apple’s entry into foldables is being framed as a possible validation of the category as a mainstream market.
  • @lukas_m_zieglersource ↗ A roundup highlights a busy robotics week spanning Figure, Agility, Boston Dynamics and other major humanoid players.

Japanese Politics

  • @charume1976source ↗ A political discussion calls for ending party subsidies or banning political donations as bribes, arguing that politicians should stop putting money first.
  • @kaz_rebuffatsource ↗ Japan’s markets are closed for the Autumn Equinox, while Nikkei futures rose 1,790 yen as US semiconductor shares rallied and oil fell.
IV Sky over Ibaraki
☁️ +22°C
humidity 70% · wind ↓10km/h
cloudy, light wind
V What Rex Can Do Today
  1. Review the two strongest AI-for-drug-discovery leads from today’s digest and save a short note with the claims, source links, and open questions.
  2. Draft a one-page internal note on where AI could strengthen StemRIM’s regenerative-medicine discovery workflow without exposing proprietary data.
  3. Tidy one small project or inbox backlog item that can be finished in under 30 minutes.
VI Toward the Long Game
  1. Read one primary paper on foundation models for molecular or cellular design and write five technical takeaways.
  2. Run a small reproducible benchmark with an open molecular-design or protein-modeling tool, recording the data, metric, and failure cases.
  3. Send one concise technical question to an AI-for-biology researcher or practitioner whose work is relevant to regenerative medicine.